Clinical Data

IRRAS is committed to providing healthcare professionals with the latest clinical evidence to demonstrate positive outcomes associated with IRRAflow use. We’ve also included available professional society guidelines and criteria that can help identify patients and disease management strategies that may benefit from Active Fluid Exchange.

Clinical Resources

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April 2025

Twist-drill craniostomy with pressure-controlled fibrinolytic irrigation therapy reduces recurrence of chronic subdural hematomas: initial experience in 16 cases

Roberto Doria-Medina, Marco Bissolo, Ralf Watzlawick, Mukesch Johannes Shah, Eva Rohr, Klaus-Jürgen Buttler, Jürgen Beck, Roland Roelz
Clinical Neurology and Neurosurgery
July 2024

Improving Outcomes in Cerebral Ventriculitis

Baig, Ammad A. MD; Hess, Ryan M. MD Sprau; Annelise C. MD, Kemeny, Hanna MD; Hashmi, Eisa B; Nazari, Pouya MD; Lim, Jaims MD; Turner, Ryan C. MD, PhD; Brandmeir, Nicholas MD, MS; Rezai Jahromi, Behnam MD; Niemelä, Mika MD, PhD; Jahromi, Babak S. MD, PhD; Levy, Elad I. MD, MBA; Siddiqui, Adnan H. MD, PhD
June 2024

Use of an Irrigating External Ventricular Drain in an Infant

Kimberly Hamilton, Nick Brandmeir, P. David Adelson
April 2024

Continuous Intrathecal Milrinone Administration via IRRAflow

Hayley Williams, Joao Gomes, and Catherine Hassett
February 2024

Stereotactic placement of dual lumen catheter systemfor continuous drainage, irrigation, and intraventricularantibiotic therapy for treatment of brain abscess withventriculitis – A case report and literature review

Domenico Policicchio, Lucio Cosco, Giuseppe Mauro, Alfonso Nicola Iannello, Luigi Santaguida, Virginia Vescio, Giosué Dipellegrini
December 2023

Continuous irrigation with thrombolytics for intraventricular hemorrhage: case–control study

Diego A. Carrera, Marc C. Mabray, Michel T. Torbey, Jason E. Andrada, Danika E. Nelson, Preeyaporn Sarangarm, Heather Spader, Chad D. Cole, Andrew P. Carlson
November 2023

Treatment of cerebral ventriculitis with a new self-irrigating catheter system: narrative review and case series

Gloria Stati, Ernesto Migliorino, Manuel Moneti, Carlo Alberto Castioni, Antonino Scibilia, Giorgio Palandri, Giulio Virgili & Raffaele Aspide
Journal of Anesthesia, Analgesia and Critical Care
October 2023

Continuous Intrathecal Medication Delivery With the IRRAflow Catheter: Pearls and Early Experience

Jeffrey Garavaglia, PharmD, BCCCP, Trevor Hardigan, MD, Ryan Turner, MD, PhD, Gracie Monachello, Muhammad Babar Khan, MD, PhD, Johnie O. Hodge, MD, PhD, Nicholas J. Brandmeir, MD, MS
Operative Neurosurgery
October 2023

HummingFlow: novel single twist-drill access for ventricular drainage, irrigation, monitoring, and automated local drug delivery in subarachnoid hemorrhage

Diego A. Carrera, MD, Laura M. Marsh, FNP, Jessica J. Roach, RN, Preeyaporn Sarangarm, PharmD, Chad D. Cole, MD, Michel T. Torbey, MD, MBA, MPH, and Andrew P. Carlson, MD
September 2023

Drainage, Irrigation, and Fibrinolytic Therapy (DRIFT) for Adult Intraventricular Hemorrhage Associated with Primary Hypertensive Hemorrhages Using IRRAflow Self-Irrigating Catheter

Nicholas C. Field, Amanda J. Custozzo, Tessa A. Harland, Jared F. Sweeney, Matthew A. Adamo, John C. Dalfino, Alexandra R. Paul
July 2023

Use of automated irrigating drainage system as rescue device for obstructive hydrocephalus in severe traumatic brain injury

June 2023

Use of Novel Automated Active Irrigation With Drainage Versus Passive Drainage Alone for Chronic Subdural Hematoma—A Propensity Score-Matched Comparative Study With Volumetric Analysis

Baig, Ammad A. MD; Hess, Ryan M. MD; Khan, Asham MD; Cappuzzo, Justin M. MD; Turner, Ryan C. MD, PhD; Hashmi, Eisa BS; Bregy, Amade MD, PhD; Kuo, Cathleen C. BS; Nyabuto, Elizabeth MD; Goyal, Aditya D. High School Diploma; Davies, Jason M. MD, PhD; Levy, Elad I. MD, MBA; Siddiqui, Adnan H. MD, PhD

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